From Heathrow Airport:
Take the Heathrow express to Paddington Station. Then take the Bakerloo Line to Oxford Street. Walk down Regents Street (toward Piccadilly Circus), turn right into Conduit Street and walk down for approx. 3 minutes. The hotel will be on your left hand side with a big tree out front (approx. 10 minutes walk).
From Gatwick Airport:
Take the Gatwick Express into Victoria Station. Take the Victoria tub line until Green Park. Now walk down Piccadilly (towards Piccadilly Circus). Turn left into Old Bond Street and walk until Conduit Street (Burberry's shop). Turn right into Conduit Street. The Westbury Mayfair will be the first building on your right (approx. 10 minutes walk).